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NABL — Nano and Artificial Biotechnology Laboratory

논문

동료 심사 논문과 학회 발표 논문입니다.

2026

Diatomite coated plate and frame filter press as novel harvest method of microalgae biomass: Design and pilot-scale study

Hyo Jik Yoon; Seung Hoon Shin; Jeong Seop Lee; Sang Jun Sim; Seung Pil Pack · Bioresource Technology · 2026

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Machine learning for scalable obstructive sleep apnea risk screening using digital phenotyping from wearable devices and clinical scales

Hyungju Kim; Sujin Kim; Ji Won Yeom; Boong-Nyun Kim; Seung Pil Pack; Heon-Jeong Lee; Taesu Cheong; Chul-Hyun Cho · Scientific Reports · 2026

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Top-Down Mass Spectrometry and Its Current Applications in Biomarker Discovery in Aging and Age-Related Diseases

Eun Ju Lee; Haneul Choi; Ki Ha Min; Hae-Min Park; Seung Pil Pack · International Journal of Molecular Sciences · 2026

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Multidimensional analysis of smartphone overuse in insomnia: Integrating digital phenotyping with clinical assessment

Emma Matsushita; Hyungju Kim; Minji Kim; Seojin Yoon; Sujin Kim; Ji Won Yeom; Seung Pil Pack; Heon-Jeong Lee; Taesu Cheong; Chul-Hyun Cho · Journal of Behavioral Addictions · 2026

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Mechanochemically Programmed, Oligomer-Selective Amyloid Assembly via Axial Rotation

Seokbeom Roh; Eunji Song; Minwoo Bae; Da Yeon Cheong; Sechan Han; Taeha Lee; Dain Kang; Jae Eon Lee; Seung Pil Pack; Hyungbeen Lee; Insu Park; Gyudo Lee · Small · 2026

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Kinetic study of glyphosate biodegradation by actinobacterial consortium RH1: implications for bioremediation

Hadjer Rebai; Rym Salah-Tazdaït; Djaber Tazdaït; Essam Nageh Sholkamy; Mohamed A. A. Abdelhamid; Seung Pil Pack; Ashraf Aly Hassan; Prakasam Thanka Pratheesh; Hazim O. Khalifa; Allaoueddine Boudemagh · Frontiers in Bioengineering and Biotechnology · 2026

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Porous and hydrophilic biosilica diatomite-embedded foam dressing: Advancing wound healing through enhanced absorption

Dong Hyun Kim; Ki Ha Min; Mi-Ran Ki; Youngji Han; Minkook Lee; Jin Hyup Lee; Seung Pil Pack · Journal of Industrial and Engineering Chemistry · 2026

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Enhancing Organic Light-Emitting Diode Performance Using Naturally Derived Diatomite: A Cost-Effective and Eco-Friendly Strategy

Chang Min Lee; Ki Ha Min; Donghyun Choi; Yeong Beom Kim; Insung Ha; Mengdi Fu; Hyun Jae Lee; Ezhakudiyan Ravindran; Chul Hoon Kim; Jeongho Lee; Kyoung-Ho Kim; Seung Pil Pack; Seung Yoon Ryu · Advanced Optical Materials · 2026

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Transcriptomic advances in studies of muscle stem cell aging: From bulk to single-cell and beyond

Soochi Kim; Seung Pil Pack; Thomas A. Rando · Cell Research · 2026

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Bipolarity as an Independent Correlate of Clinical Profiles in Insomnia: A Factorial Analysis Across Multiple Clinical Domains

Sujin Kim; Seung Pil Pack; Heon-Jeong Lee; Chul-Hyun Cho · Brain and Behavior · 2026

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Betaine-driven Keap1 methylation promotes p62-mediated autophagy and Nrf2 stabilization to alleviate glutathione-dependent redox dyshomeostasis in liver injury

Moon Han Chang; Chae Hwan Lee; Yeongrae Cho; Ryeo Gang Son; Seoyoon Lee; Shinwoo Park; Jaeryeong Kim; Young Ho Koh; Art E. Cho; Seung Pil Pack; Minseok Seo; Jin Hyup Lee; Hanvit Cha · Molecular Biomedicine · 2026

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Heart rate circadian phase and hyperarousal as wearable digital phenotyping of insomnia: An interpretable machine learning study

Minji Kim; Seojin Yun; Hyungju Kim; Emma Matsushita; Ji Won Yeom; Sujin Kim; Seung Pil Pack; Heon-Jeong Lee; Taesu Cheong; Chul-Hyun Cho · Digital Health · 2026

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Biomimetic Coacervate Coatings: From Phase Separation Fundamentals to Advanced Biomedical Applications

Ki Ha Min; Yi-Rang Jeong; Jong Won Mun; Kyu Ho Jeon; Seung Pil Pack · Biomimetics · 2026

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Stable and programmable formation of DNA nanostructures via inter-strand crosslinking by assembly-triggered oxanine and amine linkage

Jae Eon Lee; Eui Kyoung Jang; Ryeo Gang Son; Jeehyun Park; Seung Pil Pack · Nucleic Acids Research · 2026

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Long-term amyloid aggregation kinetic assay and rapid amyloid clustering enabled by programmable microdroplet water extraction

Da Yeon Cheong; Seokbeom Roh; Jung Bae Seong; Sang Won Lee; Dain Kang; Taeha Lee; Jiyeon Cho; Seung Pil Pack; Minho Moon; Wonseok Lee; Kyung Rok Nam; Bo Hyun Kim; Jae Yong Choi; Jinyoung Won; Kyung Seob Lim; Chang-Yeop Jeon; Yangzhi Zhu; Yeongjeon Lee; Gyudo Lee; Insu Park · Science Advances · 2026

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Effective harvesting of high-density microalgae biomass via combination of advanced oxidation and flocculation-flotation process

Seung Hoon Shin; Hyo Jik Yoon; Seung Pil Pack · Algal Research · 2026

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Isolation and characterization of a thermophilic Streptromyces albidoflavus strain KS5 capable of glyphosate degradation

Hadjer Rebai; Cherifa Lefaida; Essam Nageh Sholkamy; Hadel El Agamawi; Mohamed A. A. Abdelhamid; Seung Pil Pack; Hazim O. Khalifa; Allaoueddine Boudemagh · Frontiers in Microbiology · 2026

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2025

Deep phenotyping of insomnia: a multimodal assessment protocol

Yujin Lee; Seonmin Kim; Sujin Kim; Seung Pil Pack; Heon-Jeong Lee; Chul-Hyun Cho · Frontiers in Psychiatry · 2025

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Nanomaterials in Drug Delivery: Leveraging Artificial Intelligence and Big Data for Predictive Design

Youngji Han; Dong Hyun Kim; Seung Pil Pack · International Journal of Molecular Sciences · 2025

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Two-Dimensional Materials for Biosensing: Emerging Bio-Converged Strategies for Wearable and Implantable Platforms

Ki Ha Min; Koung Hee Kim; Seung Pil Pack · Chemosensors · 2025

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Fabrication and characterization of electrospun polycaprolactone/Urechis unicinctus derived-ECM composite scaffolds for small-diameter vascular grafts

Jongwon Mun; Seung Pil Pack; Hyeongjin Lee · RSC Advances · 2025

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Recent Progress in DNA Biosensors: Target-Specific and Structure-Guided Signal Amplification

Jae Eon Lee; Seung Pil Pack · Biosensors · 2025

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Economic and demonstrative pilot-scale harvesting of microalgae biomass via novel combined process of dissolved air flotation and screw-press filtration

Hyo Jik Yoon; Jeong Seop Lee; Ki Ha Min; Dong Hyun Kim; Sang Jun Sim; Seung Pil Pack · Bioresource Technology · 2025

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Feasibility and Preliminary Effectiveness of a Prototype Digital Therapeutic for Insomnia (LUIT-K): A Pilot Study

Solee Han; Seung Pil Pack; Chul-Hyun Cho · Chronobiology in Medicine · 2025

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Sustainable synthesis of zinc oxide nanoparticles from Persicaria lapathifolia: versatile anticancer and antibacterial applications

Essam Nageh Sholkamy; Mohamed A. A. Abdelhamid; Hadjer Rebai; Ananth Sivapunniyam; Mi-Ran Ki; Seung Pil Pack; Hazim O. Khalifa · Frontiers in Molecular Biosciences · 2025

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Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective Sleep Measures: Observational Cohort Study

Ji Won Yeom; Hyungju Kim; Seung Pil Pack; Heon-Jeong Lee; Taesu Cheong; Chul-Hyun Cho · JMIR Mental Health · 2025

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Fire under the ashes: A descriptive review on the prevalence of methicillin-resistant Staphylococcus aureus in the food supply chain

Hazim O. Khalifa; Mohamed A.A. Abdelhamid; Atef Oreiby; Mohamed-Yousif Ibrahim Mohamed; Hazem Ramadan; Ahmed Elfadadny; Seung Pil Pack; Han Sang Yoo; Ihab Habib · Journal of Agriculture and Food Research · 2025

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Network pharmacology and molecular docking reveal antiviral mechanisms of silver nanoparticles synthesized by Oscillatoria sp. against HCV pathogenesis

Lamya Azmy; Ebtesam Al-Olayan; Mohamed A. A. Abdelhamid; Ibraheem B. M. Ibraheem; Ahmed Zayed; Saly F. Gheda; Khayrya A. Youssif; Hesham A. Abou-Zied; Usama R. Abdelmohsen; Seung Pil Pack; Hazim O. Khalifa; Khaled N. M. Elsayed · Scientific Reports · 2025

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Coacervate formation of human bone morphogenetic protein-2 fused with an extracellular matrix peptide with hyaluronic acid

Dawoon Jeong; Hyunsuk Choi; Mi-Ran Ki; Seung Pil Pack; Yoo Seong Choi · Biotechnology and Bioprocess Engineering · 2025

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Microfluidic assessment of corticosterone-induced mitochondrial dysfunction in neuronal cells

Hyeonji Song; Huiseong Son; Huy Quoc Hoang Hua; Jae Seong Kim; Jin Hyup Lee; Seung Pil Pack; Chang-Soo Lee · Biochemical Engineering Journal · 2025

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Evaluation of mitochondrial activity via cellular interactions between adrenal and neuronal cells in a microfluidic coculture device

Jae Seong Kim; Huiseong Son; Jihun Han; Hanvit Cha; Jin Hyup Lee; Seung Pil Pack; Chang-Soo Lee · Biotechnology and Bioprocess Engineering · 2025

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Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions

Jin-Hyun Park; Yu-Bin Shin; Dooyoung Jung; Ji-Won Hur; Seung Pil Pack; Heon-Jeong Lee; Hwamin Lee; Chul-Hyun Cho · Frontiers in Psychiatry · 2025

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Low-temperature 3D-printed Aloe vera/fish-derived decellularized ECM biocomposites for wound dressing application: fabrication, characterization, and in vitro evaluation

Seong Hyun Lee; Soyoung Noh; Seung Pil Pack; GeunHyung Kim; Hyeongjin Lee · Materials & Design · 2025

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Exopolysaccharide from Lacticaseibacillus rhamnosus IR06 as a potential postbiotics attenuates photoaging through regulation of MAPK and NF-κB signaling

Jin Hwan Kim; Won June Lee; Ka Young Choi; Sang-Ho Yoo; Seung Pil Pack; Nam Su Oh · Free Radical Biology and Medicine · 2025

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Protein and Peptide in Cancer Research: From Biomarker to Biotherapeutics

Joo Hyeong Seo; Seung Hoon Shin; Hye Rin Woo; Yu Rim An; A Hyun Youn; Song Yeon Kim; Mi-Ran Ki; Seung Pil Pack · Cancers · 2025

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Microfluidic Sensors for Micropollutant Detection in Environmental Matrices: Recent Advances and Prospects

Mohamed A. A. Abdelhamid; Mi-Ran Ki; Hyo Jik Yoon; Seung Pil Pack · Biosensors · 2025

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Machine learning-based prediction of restless legs syndrome using digital phenotypes from wearables and smartphone data

Jingyeong Jeong; Yoonseo Jeon; Hyungju Kim; Ji Won Yeom; Yu-Bin Shin; Sujin Kim; Seung Pil Pack; Heon-Jeong Lee; Taesu Cheong; Chul-Hyun Cho · Scientific Reports · 2025

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Starch nanoparticle platform for oral delivery of sinigrin in colitis therapy

Hazzel Joy Adra; Hanvit Cha; Moon Han Chang; Dong-Gook Kang; Su-min Kwon; Sang-Mook You; Yu Ri Jeong; Chae Hwan Lee; Ki Sung Park; Seung Pil Pack; Jin Hyup Lee; Young-Rok Kim · Carbohydrate Polymers · 2025

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In vivo self-assembly of an intact functional cage protein: Intracellular generation of chimeric ferritins without disassembly-involved damage

Koung Hee Kim; Mi-Ran Ki; Thi Khoa My Nguyen; Ki Ha Min; Seung Pil Pack · Journal of Industrial and Engineering Chemistry · 2025

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Aptamers as Diagnostic and Therapeutic Agents for Aging and Age-Related Diseases

Tae-In Park; Ah Hyun Yang; Bashistha Kumar Kanth; Seung Pil Pack · Biosensors · 2025

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Biochar Utilization in Antimicrobial, Anticancer, and Biosensing Applications: A Review

Ki Ha Min; Koung Hee Kim; Joo-Hyung Seo; Seung Pil Pack · Biomolecules · 2025

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Biomolecule-Based Coacervation: Mechanisms, Applications, and Future Perspectives in Biomedical and Biotechnological Fields

Dong Hyun Kim; Mi-Ran Ki; Da Yeon Chung; Seung Pil Pack · Biomolecules · 2025

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Aptamer-Guided, Hydrolysis-Resistant Deoxyoxanosine Enables Epitope- and Moiety-Selective Conjugation to Nonengineered Proteins Even in Complex Environments

Hyesung Jo; Seonmin Ju; Minhye Kim; Jiyun Beon; Se-Young Jang; Seung Pil Pack; Chang Yun Son; Jong-Seo Kim; Seung Soo Oh · Journal of the American Chemical Society · 2025

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Application and Evaluation of an Eco-friendly Coagulation-flotation Microalgae Separation Process for Improving River Water Quality

Hyo Jik Yoon; Seung Hoon Shin; Ji Won Yang; Seung Pil Pack · KSBB Journal · 2025

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Cancer and Aging Biomarkers: Classification, Early Detection Technologies and Emerging Research Trends

Mi-Ran Ki; Dong Hyun Kim; Mohamed A. A. Abdelhamid; Seung Pil Pack · Biosensors · 2025

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Ajuba as a Potential Nutrition-Responsive Biomarker for the Prevention of Age-Related Sarcopenia

Youngji Han; Seung Pil Pack · International Journal of Molecular Sciences · 2025

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Bioinformation and Monitoring Technology for Environmental DNA Analysis: A Review

Hyo Jik Yoon; Joo Hyeong Seo; Seung Hoon Shin; Mohamed A. A. Abdelhamid; Seung Pil Pack · Biosensors · 2025

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2024

Biomineral-Based Composite Materials in Regenerative Medicine

Sung Ho Kim; Mi-Ran Ki; Youngji Han; Seung Pil Pack · International Journal of Molecular Sciences · 2024

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Nanoengineered Silica-Based Biomaterials for Regenerative Medicine

Mohamed A. A. Abdelhamid; Hazim O. Khalifa; Mi-Ran Ki; Seung Pil Pack · International Journal of Molecular Sciences · 2024

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Transcriptional regulation of multi-tissue mRNA expression by L-arabinose mitigates metabolic disorders in leptin receptor-deficient mice

Youngji Han; Yuri Jeong; Jin Hyup Lee; Seung Pil Pack · Food Bioscience · 2024

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Size Control of Biomimetic Curved-Edge Vaterite with Chiral Toroid Morphology via Sonochemical Synthesis

Ki Ha Min; Dong Hyun Kim; Seung Pil Pack · Biomimetics · 2024

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Bioinspired Synthesis and Characterization of Dual-Function Zinc Oxide Nanoparticles from Saccharopolyspora hirsuta: Exploring Antimicrobial and Anticancer Activities

Essam N. Sholkamy; Mohamed A. A. Abdelhamid; Hazim O. Khalifa; Mi-Ran Ki; Seung Pil Pack · Biomimetics · 2024

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Marine-Derived Bioactive Ingredients in Functional Foods for Aging: Nutritional and Therapeutic Perspectives

Youngji Han; Dong Hyun Kim; Seung Pil Pack · Marine Drugs · 2024

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RNA sequencing analysis of sexual dimorphism in Japanese quail

Sinwoo Park; Jaeryeong Kim; Jinbaek Lee; Sungyoon Jung; Seung Pil Pack; Jin Hyup Lee; Kyungheon Yoon; Seung Je Woo; Jae Yong Han; Minseok Seo · Frontiers in Veterinary Science · 2024

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Soil Actinobacteria Exhibit Metabolic Capabilities for Degrading the Toxic and Persistent Herbicide Metribuzin

Hadjer Rebai; Essam Nageh Sholkamy; Mohamed A. A. Abdelhamid; Pratheesh Prakasam Thanka; Ashraf Aly Hassan; Seung Pil Pack; Mi-Ran Ki; Allaoueddine Boudemagh · Toxics · 2024

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Biosilica-coated carbonic anhydrase displayed on Escherichia coli: A novel design approach for efficient and stable biocatalyst for CO2 sequestration

Mohamed A.A. Abdelhamid; Ryeo Gang Son; Mi-Ran Ki; Seung Pil Pack · International Journal of Biological Macromolecules · 2024

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Biominerals and Bioinspired Materials in Biosensing: Recent Advancements and Applications

Mohamed A. A. Abdelhamid; Mi-Ran Ki; Seung Pil Pack · International Journal of Molecular Sciences · 2024

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Microalgae-derived peptide with dual-functionalities of silica deposition and antimicrobial activity for biosilica-based biomaterial design

Ki Ha Min; Dong Hyun Kim; Jin Woo Shin; Mi-Ran Ki; Seung Pil Pack · Process Biochemistry · 2024

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Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin

Sol Youn; Mi-Ran Ki; Mohamed A. A. Abdelhamid; Seung-Pil Pack · Biomimetics · 2024

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Fluorometric and Colorimetric Method for SARS-CoV-2 Detection Using Designed Aptamer Display Particles

Ki Sung Park; Anna Choi; Tae-In Park; Seung Pil Pack · Biosensors · 2024

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Biomimetic Antifungal Materials: Countering the Challenge of Multidrug-Resistant Fungi

Hazim O. Khalifa; Atef Oreiby; Mohamed A. A. Abdelhamid; Mi-Ran Ki; Seung Pil Pack · Biomimetics · 2024

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Mechanistic insight into airborne particulate matter PM10 as an environmental hazard for hemorrhagic stroke: Evidence from in vitro and in vivo studies

Chae Hwan Lee; Moon Han Chang; Young Ho Koh; Seung Pil Pack; Minseok Seo; Hanvit Cha; Jin Hyup Lee · Journal of Hazardous Materials · 2024

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Preventive effect of fermented whey protein mediated by Lactobacillus gasseri IM13 via the PI3K/AKT/FOXO pathway in muscle atrophy

Ji Hun Jang; Jae Yeon Joung; Seung Pil Pack; Nam Su Oh · Journal of Dairy Science · 2024

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Aptamers and Nanobodies as New Bioprobes for SARS-CoV-2 Diagnostic and Therapeutic System Applications

Ki Sung Park; Tae-In Park; Jae Eon Lee; Seo-Yeong Hwang; Anna Choi; Seung Pil Pack · Biosensors · 2024

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Microbial Immobilized Enzyme Biocatalysts for Multipollutant Mitigation: Harnessing Nature's Toolkit for Environmental Sustainability

Mohamed A. A. Abdelhamid; Hazim O. Khalifa; Hyo Jik Yoon; Mi-Ran Ki; Seung Pil Pack · International Journal of Molecular Sciences · 2024

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DNA-controlled protein fluorescence: Design of aptamer-split peptide hetero-modulator for GFP to respond to intracellular ATP levels

Ki Sung Park; Hanvit Cha; Jia Niu; Hyongsok Tom Soh; Jin Hyup Lee; Seung Pil Pack · Nucleic Acids Research · 2024

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Biomimetic Scaffolds of Calcium-Based Materials for Bone Regeneration

Ki Ha Min; Dong Hyun Kim; Koung Hee Kim; Joo-Hyung Seo; Seung Pil Pack · Biomimetics · 2024

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Natural Compounds for Preventing Age-Related Diseases and Cancers

Mi-Ran Ki; Sol Youn; Dong Hyun Kim; Seung Pil Pack · International Journal of Molecular Sciences · 2024

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Efficient Bioactive Surface Coatings with Calcium Minerals: Step-Wise Biomimetic Transformation of Vaterite to Carbonated Apatite

Dong Hyun Kim; Ki Ha Min; Seung Pil Pack · Biomimetics · 2024

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Antimicrobial Activity of Arthrospira platensis-Mediated Gold Nanoparticles against Streptococcus pneumoniae: A Metabolomic and Docking Study

Lamya Azmy; Ebtesam Al-Olayan; Mohamed A. A. Abdelhamid; Ahmed Zayed; Saly F. Gheda; Khayrya A. Youssif; Hesham A. Abou-Zied; Usama R. Abdelmohsen; Ibraheem B. M. Ibraheem; Seung Pil Pack; Khaled N. M. Elsayed · International Journal of Molecular Sciences · 2024

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Antimicrobial and Hemostatic Diatom Biosilica Composite Sponge

Sol Youn; Mi-Ran Ki; Ki Ha Min; Mohamed A. A. Abdelhamid; Seung Pil Pack · Antibiotics · 2024

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Antimicrobial Peptides and Their Biomedical Applications: A Review

Ki Ha Min; Koung Hee Kim; Mi-Ran Ki; Seung Pil Pack · Antibiotics · 2024

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Biomimetic Diatom Biosilica and Its Potential for Biomedical Applications and Prospects: A Review

Ki Ha Min, Dong Hyun Kim, Sol Youn andSeung Pil Pack · INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES · 2024

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Use of biosilica to improve loading and delivery of bone morphogenic protein 2

Mi-Ran Ki, Sung Ho Kim, Seokbeom Rho, Jong Ki Kim, Ki Ha Min, Ki Baek Yeo, Jaewook Lee, Gyudo Lee, Sang-Ho Jun, Seung Pil Pack · INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2024

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2023

Green synthesis of silver nanoparticles on biosilica diatomite: Well-dispersed particle formation and reusability

Ki Ha Min, Jin Woo Shin, Mi-Ran Ki, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2023

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Sensitization of GSH synthesis by curcumin curtails acrolein-induced alveolar epithelial apoptosis via Keap1 cysteine conjugation: A randomized controlled trial and experimental animal model of pneumonitis

Eun Hee Jo, Ji Eun Moon, Moon Han Chang, Ye Jin Lim, Jung Hyun Park, Suk Hee Lee, Young Rae Cho, Art E Cho, Seung Pil Pack, Hyeon-Wee Kim, Liana Crowley, Brandy Le, Aykin-Burns Nukhet, Yinfeng Chen, Yihang Zhong, Jiangchao Zhao, Ying Li, Hanvit Cha, Jeong Hoon Pan, Jae Kyeom Kim, Jin Hyup Lee · JOURNAL OF ADVANCED RESEARCH · 2023

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Advanced Delivery System of Polyphenols for Effective Cancer Prevention and Therapy

Koung Hee Kim, Mi-Ran Ki, Ki Ha Min, Seung Pil Pack · ANTIOXIDANTS · 2023

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Novel silicatein-like protein for biosilica production from Amphimedon queenslandica and its use in osteogenic composite fabrication

Mi-Ran Ki, Ki Sung Park, Mohamed A. A. Abdelhamid & Seung Pil Pack · KOREAN JOURNAL OF CHEMICAL ENGINEERING · 2023

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Self-Entrapment of Antimicrobial Peptides in Silica Particles for Stable and Effective Antimicrobial Peptide Delivery System

Mi-Ran Ki, Sung Ho Kim, Tae In Park and Seung Pil Pack · INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES · 2023

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Biomimetic Silica Particles with Self-Loading BMP-2 Knuckle Epitope Peptide and Its Delivery for Bone Regeneration

Mi-Ran Ki,Thi Khoa My Nguyen, Tae-In Park, Hae-Min Park, Seung Pil Pack · PHARMACEUTICS · 2023

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Ultra-sensitive label-free SERS biosensor with high-throughput screened DNA aptamer for universal detection of SARS-CoV-2 variants from clinical samples

Ki Sung Park, Anna Choi, Hyun Jung Kim, Insu Park, Mi-Suk Eom, Sang-Gu Yeo, Ryeo Gang Son, Tae-In Park, Gyudo Lee, Hyongsok Tom Soh, Yoochan Hong, Seung Pil Pack · BIOSENSORS & BIOELECTRONICS · 2023

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Tailored Functionalized Protein Nanocarriers for Cancer Therapy: Recent Developments and Prospects

Mohamed A. A. Abdelhamid, Mi-Ran Ki, Amer Ali Abd El-Hafeez, Ryeo Gang Son and Seung Pil Pack · PHARMACEUTICS · 2023

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Elucidating TH301's influence on the torsion angle of CRY1 W399 using replica exchange with solute tempering (REST) molecular dynamics (MD) simulations

Yeongrae Cho, Kexin Li, Jin Hyup Lee, Seung Pil Pack and Art E. Cho · PHYSICAL CHEMISTRY CHEMICAL PHYSICS · 2023

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Machine Learning-Based Prediction of Attention-Deficit/Hyperactivity Disorder and Sleep Problems With Wearable Data in Children

Won-Pyo Kim, Hyun-Jin Kim, Seung Pil Pack, Jae-Hyun Lim, Chul-Hyun Cho, Heon-Jeong Lee · JAMA NETWORK OPEN · 2023

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Noise-reduced nicking enzyme-based isothermal amplification via blocking the 3'-end of the amplicon using a novel fluorophore-immobilized binder

Eui Kyoung Jang, Myong Jin Lee, Jinsik Kim, Jae Woo Lee, Seung Pil Pack · SENSORS AND ACTUATORS B-CHEMICAL · 2023

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Benchmark study for evaluating the quality of reference genomes and gene annotations in 114 species

Sinwoo Park, Jinbaek Lee, Jaeryeong Kim, Dohyeon Kim, Jin Hyup Lee, Seung Pil Pack, Minseok Seo · FRONTIERS IN VETERINARY SCIENCE · 2023

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2022

Chimeric protein-mediated dual mineral formation on biopolymer: Non-segregated and well-distributed deposition of CaCO3 and silica particles

Sung Ho Kim; Mi-Ran Ki; Ki Sung Park; Ki Baek Yeo; Seung Pil Pack · Colloids and Surfaces B: Biointerfaces · 2022

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pH-responsive phototherapeutic poly(acrylic acid)-calcium phosphate passivated TiO2 nanoparticle-based drug delivery system for cancer treatment applications

Jihoon Han, Eui-Kyung Jang, Mi-Ran Ki,Ryeo Gang Son, Seok Kim, Youngson Choe, Seung Pil Pack, Sungwook Chung · JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY · 2022

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BMP2-Mediated Silica Deposition: An Effective Strategy for Bone Mineralization

Mi-Ran Ki, Sung Ho Kim, Thi Khoa My Nguyen, Ryeo Gang Son, Sang Ho Jun, and Seung Pil Pack · ACS Biomaterials Science & Engineering · 2022

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Cordyceps mushroom with increased cordycepin content by the cultivation on edible insects

Ayman Turk, Mohamed A. A. Abdelhamid, Sang Won Yeon, Se Hwan Ryu, Solip Lee, Sung Min Ko, Beom Seok Kim, Seung Pil Pack, Bang Yeon Hwang and Mi Kyeong Lee · FRONTIERS IN MICROBIOLOGY · 2022

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Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway

Amer Ali Abd El-Hafeez, Hala Mohamed M. Marzouk, Mohamed A. A. Abdelhamid, Hazim O. Khalifa, Tamer H. A. Hasanin, Ahmed G. K. Habib, Fatma Mahmoud Abdelwahed, Fatma M. Barakat, Eslam M. Bastawy, Eman M. B. Abdelghani, Toru Hosoi, Koichiro Ozawa, Ahmed M. Aref, Takashi Fujimura, Ahmed R. N. Ibrahim, Aalaa S. O. Abdelmoniem, Hagar Elghazawy, Pradipta Ghosh, Seiji Kawamoto & Seung Pil Pack · BIOTECHNOLOGY AND BIOPROCESS ENGINEERING · 2022

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Colorimetric Sensing of Lactate in Human Sweat Using Polyaniline Nanoparticles-Based Sensor Platform and Colorimeter

Hyun Jung Kim, Insu Park,Seung Pil Pack, Gyudo Lee and Yoochan Hong · BIOSENSORS-BASEL · 2022

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Oriented multivalent silaffin-affinity immobilization of recombinant lipase on diatom surface: Reliable loading and high performance of biocatalyst

Mohamed A.A. Abdelhamid, Ryeo Gang Son, Ki Sung Park, Seung Pil Pack · COLLOIDS AND SURFACES B-BIOINTERFACES · 2022

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Soluble preparation and characterization of tripartite split GFP for In Vitro reconstitution applications

Ki Sung Park, Ryeo Gang Son, Sung Ho Kim, Mohamed A.A. Abdelhamid, Seung Pil Pack · BIOCHEMICAL ENGINEERING JOURNAL · 2022

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Prediction of Specific Anxiety Symptoms and Virtual Reality Sickness Using In Situ Autonomic Physiological Signals During Virtual Reality Treatment in Patients With Social Anxiety Disorder: Mixed Methods Study

Joo Young Chun, Hyun-Jin Kim, Ji-Won Hur, Dooyoung Jung, Heon-Jeong Lee, Seung Pil Pack, Sungkil Lee, Gerard Kim, Chung-Yean Cho, Seung-Moo Lee, Hyeri Lee, Seungmoon Choi, Taesu Cheong, Chul-Hyun Cho · JMIR SERIOUS GAMES · 2022

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Recent progress in flocculation, dewatering, and drying technologies for microalgae utilization: Scalable and low-cost harvesting process development

Ki Ha Min, Dong Hyun Kim, Mi-Ran Ki, Seung Pil Pack · BIORESOURCE TECHNOLOGY · 2022

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2021

Carbonic Anhydrase as CO2 capturing agent: its Classes and Catalytic Mechanisms

Bashistha Kumar Kanth; Seung Pil Pack · International Journal of Mathematics and Computers in Simulation · 2021

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Synthesis of sub-50 nm bio-inspired silica particles using a C-terminal-modified ferritin template with a silica-forming peptide

Thi Khoa My Nguyen, Mi Ran Ki, Ryeo Gang Son, Kyung Hee Kim, Junghwa Hong, Seung Pil Pack · JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY · 2021

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Osteostimulating Ability of beta-tricalcium Phosphate/collagen Composite as a Practical Bone-grafting Substitute: In vitro and in vivo Comparison Study with Commercial One

En-ji Cheon, Sung-Ho Kim, Dong-Keon Lee, Yun-Kee Jo, Mi-Ran Ki, Chang-Joo Park, Hyon-Seok Jang, Jin-Soo Ahn, Seung-Pil Pack & Sang-Ho Jun · BIOTECHNOLOGY AND BIOPROCESS ENGINEERING · 2021

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Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone-graft substitute for accelerated craniofacial bone regeneration

Dong Keon Lee, Mi-Ran Ki, Euy Hyun Kim, Chang-Joo Park, Jae Jun Ryu, Hyon Seok Jang, Seung Pil Pack, Yun Kee Jo & Sang Ho Jun · BIOMATERIALS RESEARCH · 2021

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Tyrosinase-mediated rapid and permanent chitosan/gelatin and chitosan/gelatin/nanohydroxyapatite hydrogel

Sujin Lim, Dawoon Jeong, Mi-Ran Ki, Seung Pil Pack & Yoo Seong Choi · KOREAN JOURNAL OF CHEMICAL ENGINEERING · 2021

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Biomimetic and bioinspired silicifications: Recent advances for biomaterial design and applications

Mohamed A.A.Abdelhamidab, Seung PilPack · ACTA BIOMATERIALIA · 2021

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Bone Graft Biomineral Complex Coderived from Marine Biocalcification and Biosilicification

Jinyoung Yun, Yeonsu Jeong, Onyou Nam, Ki Baek Yeo, Yun Kee Jo, Hye Ryoung Heo, Chang Sup Kim, Kye Il Joo, Seung Pil Pack, EonSeon Jin, and Hyung Joon Cha · ACS APPLIED BIO MATERIALS · 2021

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Bio-inspired formation of silica particles using the silica-forming peptides found by silica-binding motif sequence, RRSSGGRR

Ki Ha Min, Jin Woo Shin, Mi-Ran Ki, Sung Ho Kim, Kyung Hee Kim, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2021

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Effect of Human or Mouse IL-7 on the Homeostasis of Porcine T Lymphocytes

Ji Hwa Hong, Sang Hoon Kim, Hyun Gyung Kim, Jun Ho Jang, Ryeo Gang Son, Seung Pil Pack, Young-Ho Park Philyong Kang, Kang-Jin Jeong, Ji-Su Kim, Hanbyeul Choi, Sun-Uk Kim, Yong Woo Jung · IMMUNE NETWORK · 2021

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2020

A dual-functional peptide, Kpt from Ruegeria pomeroyi DSS-3 for protein purification and silica precipitation

Thi Khoa My Nguyen, Mi Ran Ki, Ryeo Gang Son, Kyung Hee Kim, Junghwa Hong, Seung Pil Pack · BIOCHEMICAL ENGINEERING JOURNAL · 2020

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Solvo-hydrothermal synthesis of calcium phosphate nanostructures from calcium inositol hexakisphosphate precursor in water-ethanol mixed solutions

Ji-Hoon Han, Seung Pil Pack & Sungwook Chung · KOREAN JOURNAL OF CHEMICAL ENGINEERING · 2020

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Nucleobase-involved native chemical ligation: a novel reaction between an oxanine nucleobase and N-terminal cysteine for oligonucleotide-peptide conjugation

Eui Kyoung Jang, Yohei Koike, Yuko Ide, Kunihiko Tajima, Kenji Kanaoriand Seung Pil Pack · CHEMICAL COMMUNICATIONS · 2020

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Compartment-restricted and rate-controlled dual drug delivery system using a biosilica-enveloped ferritin cage

Mi-Ran Ki, Jong Ki Kim, Sung Ho Kim, Thi Khoa My Nguyen, Kyung Hee Kim, Seung Pil Pack · JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY · 2020

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Production of TiO2-deposited Diatoms and Their Applications for Photo-catalytic Degradation of Aqueous Pollutants

Kumari Shipra, Ki Ha Min, Kanth Bashistha Kumar, Eui Kyoung Jang, Seung Pil Pack · BIOTECHNOLOGY AND BIOPROCESS ENGINEERING · 2020

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A systematic study of hexavalent chromium adsorption and removal from aqueous environments using chemically functionalized amorphous and mesoporous silica nanoparticles

Eun-Hye Jang, Seung Pil Pack, Il Kim & Sungwook Chung · SCIENTIFIC REPORTS · 2020

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Fusion tags to enhance heterologous protein expression

Mi-Ran Ki, Seung Pil Pack · APPLIED MICROBIOLOGY AND BIOTECHNOLOGY · 2020

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Silaffin-3-derived pentalysine cluster as a new fusion tag for one-step immobilization and purification of recombinant Bacillus subtilis catalase on bare silica particles

Mohamed A.A.Abdelhamid, Alaa M.A.Meligy, Ki Baek Yeo, Chang-Soo Lee, Seung Pil Pack · INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2020

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Novel silica forming peptide, RSGH, from Equus caballus: Its unique biosilica formation under acidic conditions

Ki Ha Min, Ki Baek Yeo, Mi-Ran Ki, Sang Ho Jun, Seung Pil Pack · BIOCHEMICAL ENGINEERING JOURNAL · 2020

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Stabilized and Immobilized Carbonic Anhydrase on Electrospun Nanofibers for Enzymatic CO2 Conversion and Utilization in Expedited Microalgal Growth

Seung-Hyun Jun, Jusang Yang, Hancheol Jeon, Han Sol Kim, Seung Pil Pack, EonSeon Jin, and Jungbae Kim · ENVIRONMENTAL SCIENCE & TECHNOLOGY · 2020

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2019

Nanosized and tunable design of biosilica particles using novel silica-forming peptide-modified chimeric ferritin templates

Thi Khoa My Nguyen, Mi Ran Ki, Chang Soo Lee, Seung Pil Pack · JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY · 2019

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The NT11, a novel fusion tag for enhancing protein expression in Escherichia coli

Thi Khoa My Nguyen, Mi Ran Ki, Ryeo Gang Son, Seung Pil Pack · APPLIED MICROBIOLOGY AND BIOTECHNOLOGY · 2019

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Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-kappa B, and STAT3

Amer Ali Abd El-Hafeez, Hazim O Khalifa, Elham A M Mahdy, Vikas Sharma, Toru Hosoi, Pradipta Ghosh, Koichiro Ozawa, Monica M Montano, Takashi Fujimura, Ahmed R N Ibrahim, Mohamed A A Abdelhamid, Seung Pil Pack, Samia A Shouman, Seiji Kawamoto · PHARMACOLOGICAL REPORTS · 2019

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Direct immobilization and recovery of recombinant proteins from cell lysates by using EctP1-peptide as a short fusion tag for silica and titania supports

Jong Ki Kim, Mohamed A A Abdelhamid, Seung Pil Pack · INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2019

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Self-encapsulation and controlled release of recombinant proteins using novel silica-forming peptides as fusion linkers

Mohamed A.A.Abdelhamid, Ki Baek Yeo, Mi-Ran Ki, Seung Pil Pack · INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2019

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Novel enzymatic single-nucleotide modification of DNA oligomer: prevention of incessant incorporation of nucleotidyl transferase by ribonucleotide-borate complex

Eui Kyoung Jang, Ryeo Gang Son, Seung Pil Pack · NUCLEIC ACIDS RESEARCH · 2019

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2018

Biosilica-enveloped ferritin cage for more efficient drug deliveries

Mi-Ran Ki, Thi Khoa My Nguyen, Hyun Sik Jun, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2018

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Stabilization of Bovine carbonic anhydrase II through rational site-specific immobilization

Chang Hyun Lee, Eui Kyoung Jang, Young Joo Yeon, Seung Pil Pack · BIOCHEMICAL ENGINEERING JOURNAL · 2018

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Decreased Expression of Sphingosine-1-Phosphate Receptor 1 in the Blood Leukocyte of Rheumatoid Arthritis Patients

Hyun Suk Choi, Kyong Hoon Kim, Seohoon Jin, Jinhyun Kim, Inseol Yoo, Seung Pil Pack, Un-Hwan Ha, Tae Won Park, Soo An Choi, Soon Hong Yuk, Seong Wook Kang and Yong Woo Jung · IMMUNE NETWORK · 2018

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Solvothermal synthesis and characterization of highly monodisperse organically functionalized vanadium oxide nanocrystals for thermochromic applications

Yu-Hong Jung, Seung Pil Pack, Sung wook Chung · MATERIALS RESEARCH BULLETIN · 2018

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Improvement in the Reproducibility of a Paper-based Analytical Device (PAD) Using Stable Covalent Binding between Proteins and Cellulose Paper

Woogyeong Hong, Seong-Geun Jeong, Gyurak Shim, Dae Young Kim, Seung Pil Pack & Chang-Soo Lee · BIOTECHNOLOGY AND BIOPROCESS ENGINEERING · 2018

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2017

Increased incorporation of gaseous CO2 into succinate by Escherichia coil overexpressing carbonic anhydrase and phosphoenolpyruvate carboxylase genes

Soohyun Park, Jae-Ung Lee, Sukhyeong Cho, Hyeonsoo Kim, Han Bin Oh, Seung Pil Pack, Jinwon Lee · JOURNAL OF BIOTECHNOLOGY · 2017

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Design of reactive-end DNA oligomers via incorporation of oxanine into oligonucleotides using terminal deoxynucleotidyl transferase

Eui Kyoung Jang, Mi-Ran Ki, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2017

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In-depth compositional analysis of water-soluble and -insoluble organic substances in fine (PM2.5) airborne particles using ultra-high resolution 15T FT-ICR MS and GCx GC-TOFMS

Jung Hoon Choi, Jijeong Ryu, Sodam Jeon, Jungju Seo, Yung-Hun Yang, SeungPil Pack, Sungwook Choung, Kyoung-Soon Jang · ENVIRONMENTAL POLLUTION · 2017

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Design of bio-inspired silica-encapsulated protein A for improved immunoprecipitation assays

Ki Sung Park, Mi-Ran Ki, Ki Baek Yeo, Jung Hoon Choi, Seung Pil Pack · BIOCHEMICAL ENGINEERING JOURNAL · 2017

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Chemical characterization of dissolved organic matter in moist acidic tussock tundra soil using ultra-high resolution 15T FT-ICR mass spectrometry

Jung Hoon Choi, Yun-Gon Kim, Yoo Kyung Lee, Seung Pil Pack, Ji Young Jung & Kyoung-Soon Jang · BIOTECHNOLOGY AND BIOPROCESS ENGINEERING · 2017

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Novel silica-forming peptides derived from Ectocarpus siliculosus

Ki Baek Yeo, Mi-Ran Ki, Ki Sung Park, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2017

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Expression and characterization of a codon-optimized alkaline-stable carbonic anhydrase from Aliivibrio salmonicida for CO2 sequestration applications

So-Young Jun, Sung Ho Kim, Bashista Kumar Kanth, Jinwon Lee, Seung Pil Pack · BIOPROCESS AND BIOSYSTEMS ENGINEERING · 2017

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2016

Recombinant production of a shell matrix protein in Escherichia coli and its application to the biomimetic synthesis of spherulitic calcite crystals

Wooho Song, So Yeong Bahn, Hyung Joon Cha, Seung Pil Pack, Yoo Seong Choi · BIOTECHNOLOGY LETTERS · 2016

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A cold-adapted tyrosinase with an abnormally high monophenolase/diphenolase activity ratio originating from the marine archaeon Candidatus Nitrosopumilus koreensis

Hyerin Kim, Young Joo Yeon, Yoo Rae Choi, Wooho Song, Seung Pil Pack, Yoo Seong Choi · BIOTECHNOLOGY LETTERS · 2016

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The role of extracellular polymeric substances in reducing copper inhibition to nitrification in activated sludge

June S. Song, Minho Maeng, Kwanhyung Lee, Seung Pil Pack & Jae Woo Lee · BIOTECHNOLOGY AND BIOPROCESS ENGINEERING · 2016

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Ammonia-based plasma treatment of single-walled carbon nanotube thin films for bio-immobilization

Jaemin Lee, Alexander Efremov, Ryeo Gang Son, Seung Pil Pack, Hyun Woo Lee, Kwangsoo Kim, Kwang-Ho Kwon · CARBON · 2016

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Chimeric protein of internally duplicated alpha-type carbonic anhydrase from Dunaliella species for improved expression and CO2 sequestration

Mi-Ran Ki, Thi Khoa My Nguyen, Sung Ho Kim, Inchan Kwon, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2016

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High expression and biosilica encapsulation of alkaline-active carbonic anhydrase for CO2 sequestration system development

Ki-Ha Min, Ryeo Gang Son, Mi-Ran Ki, Yoo Seong Choi, Seung Pil Pack · CHEMOSPHERE · 2016

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Positional effects of hydrophobic non-natural amino acid mutagenesis into the surface region of murine dihydrofolate reductase on enzyme properties

H. Edward Wong, Seung Pil Pack, Inchan Kwon · BIOCHEMICAL ENGINEERING JOURNAL · 2016

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Highly effective detection of inflamed cells using a modified bradykinin ligand labeled with FITC fluorescence

Ki Baek Yeo, Hyong Bai Kim, Yoo Seong Choi, Seung Pil Pack · ENZYME AND MICROBIAL TECHNOLOGY · 2016

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Improved stability and reusability of endoglucanase from Clostridium thermocellum by a biosilica-based auto-encapsulation method

Young Ha Ryu, Ki Baek Yeo, Mi-Ran Ki, Yong Jun Kim, Seung Pil Pack · BIOCHEMICAL ENGINEERING JOURNAL · 2016

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2015

Characterization of Phosphoenolpyruvate Carboxylase from Oceanimonas smirnovii in Escherichia coli

Soohyun Park, Wangjun Lee, Hyeonsoo Kim, Seung Pil Pack, Jinwon Lee · APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY · 2015

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Highly-efficient T4 DNA ligase-based SNP analysis using a ligation fragment containing a modified nucleobase at the end

Eui Kyoung Jang, Munhee Yang and Seung Pil Pack · CHEMICAL COMMUNICATIONS · 2015

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2014

Enhanced free fatty acid production by codon-optimized Lactococcus lactis acyl-ACP thioesterase gene expression in Escherichia coli using crude glycerol

Sunhee Lee, Soohyun Park, Chulhwan Park, Seung Pil Pack, Jinwon Lee · ENZYME AND MICROBIAL TECHNOLOGY · 2014

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High-throughput diatom counting method based on lens-free shadow image analysis

Hyeon Soo Jeong, Eui Kyoung Jang, Geon Soo Jin, Sungkyu Seo, Seung Pil Pack · SENSORS AND ACTUATORS B-CHEMICAL · 2014

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Hypothetical cathepsin-like protein from Nematostella vectensis and its silicatein-like cathepsin mutant for biosilica production

Mi-Ran Ki, Eui-Kyung Jang, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2014

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High activity and stability of codon-optimized phosphoenolpyruvate carboxylase from Photobacterium profundum SS9 at low temperatures and its application for in vitro production of oxaloacetate

Soohyun Park, Soohye Hong, Seung Pil Pack, Jinwon Lee · BIOPROCESS AND BIOSYSTEMS ENGINEERING · 2014

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A multiplex single nucleotide polymorphism genotyping method using ligase-based mismatch discrimination and CE-SSCP

Woong Choi, Gi Won Shin, Hee Sung Hwang, Seung Pil Pack, Gyu Yong Jung, Gyoo Yeol Jung · ELECTROPHORESIS · 2014

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Bioinspired Silica Nanocomposite with Autoencapsulated Carbonic Anhydrase as a Robust Biocatalyst for CO2 Sequestration

Byung Hoon Jo, Jeong Hyun Seo, Yun Jung Yang, Kyungjoon Baek, Yoo Seong Choi, Seung Pil Pack, Sang Ho Oh, and Hyung Joon Cha · ACS CATALYSIS · 2014

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CO2 gas conversion to oxaloacetate by Escherichia coli harboring codon-optimized carbonic anhydrase and phosphoenolpyruvate carboxylase derived from marine bacteria

Soohyun Park, Soohye Hong, Sangwoo Kim, Seung Pil Pack, Jinwon Lee · NEW BIOTECHNOLOGY · 2014

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Highly thermostable carbonic anhydrase from Persephonella marina EX-H1: Its expression and characterization for CO2-sequestration applications

Bashistha Kumar Kanth, So-Young Jun, Shipra Kumari, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2014

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Diverse Influences of Androgen-Disrupting Chemicals on Immune Responses Mounted by Macrophages

Kyong Hoon Kim, Seung-min Yeon, Hyun Gyung Kim, Hyun Suk Choi, Hyojeung Kang, Hee-Deung Park, Tae Won Park, Seung Pil Pack, Eun Hee Lee, Youngjoo Byun, Sang-Eun Choi, Kenneth Sung Lee, Un-Hwan Ha, Yong Woo Jung · INFLAMMATION · 2014

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2013

Conversion of carbon dioxide to oxaloacetate using integrated carbonic anhydrase and phosphoenolpyruvate carboxylase

Kwang Suk Chang, Hancheol Jeon, Man Bock Gu, Seung Pil Pack & EonSeon Jin · BIOPROCESS AND BIOSYSTEMS ENGINEERING · 2013

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Specific detection of inflamed cells using TLR1 antibody and its secondary antibody-conjugated nano-beads

Ki Baek Yeo, Unhwan Ha, Yong Woo Jung, Taek Jin Kang, Seung Pil Pack · ENZYME AND MICROBIAL TECHNOLOGY · 2013

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Expression, reconstruction and characterization of codon-optimized carbonic anhydrase from Hahella chejuensis for CO2 sequestration application

Mi-Ran Ki, Kiha Min, Bashistha Kumar Kanth, Jinwon Lee, Seung Pil Pack · BIOPROCESS AND BIOSYSTEMS ENGINEERING · 2013

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Buffer-free production of gamma-aminobutyric acid using an engineered glutamate decarboxylase from Escherichia coli

Taek Jin Kang, Ngoc Anh Thu Ho, Seung Pil Pack · ENZYME AND MICROBIAL TECHNOLOGY · 2013

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Pulsed dipole radiation in a transformation-optics wedge waveguide designed by azimuthal space compression

Heungjoon Kim, Seung Pil Pack, Yun Yi, and Hwi Kim · OPTICS EXPRESS · 2013

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Translocation and Stability of Replicative DNA Helicases upon Encountering DNA-Protein Cross-links

Toshiaki Nakano, Mayumi Miyamoto-Matsubara, Mahmoud I. Shoulkamy, Amir M. H. Salem, Seung Pil Pack, Yukio Ishimi, and Hiroshi Ide · JOURNAL OF BIOLOGICAL CHEMISTRY · 2013

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Surface immobilization of protein via biosilification catalyzed by silicatein fused to glutathione S-transferase (GST)

Mi-Ran Ki, Ki Baek Yeo, Seung Pil Pack · BIOPROCESS AND BIOSYSTEMS ENGINEERING · 2013

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Cyclization tag for the detection and facile purification of backbone-cyclized proteins

Pamidimarri D V N Sudheer, Seung Pil Pack, Taek Jin Kang · ANALYTICAL BIOCHEMISTRY · 2013

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Carbonic anhydrase: Its biocatalytic mechanisms and functional properties for efficient CO2 capture process development

Bashistha Kumar Kanth, Jinwon Lee, Seung Pil Pack · ENGINEERING IN LIFE SCIENCES · 2013

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Protein Thermostabilizing Factors: High Relative Occurrence of Amino Acids, Residual Properties, and Secondary Structure Type in Different Residual State

Seung Pil Pack, Taek Jin Kang, Young Je Yoo · APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY · 2013

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Oxaloacetate and malate production in engineered Escherichia coli by expression of codon-optimized phosphoenolpyruvate carboxylase2 gene from Dunaliella salina

Soohyun Park, Kwang Suk Chang, Eonseon Jin, Seung Pil Pack, Jinwon Lee · BIOPROCESS AND BIOSYSTEMS ENGINEERING · 2013

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2012

Solution structure and stability of the DNA undecamer duplexes containing oxanine mismatch

Seung Pil Pack, Hirohisa Morimoto, Keisuke Makino, Kunihiko Tajima, Kenji Kanaori · NUCLEIC ACIDS RESEARCH · 2012

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T7 RNA Polymerases Backed up by Covalently Trapped Proteins Catalyze Highly Error Prone Transcription

Toshiaki Nakano, Ryo Ouchi, Junya Kawazoe, Seung Pil Pack, Keisuke Makino, Hiroshi Ide · JOURNAL OF BIOLOGICAL CHEMISTRY · 2012

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Increased expression level and catalytic activity of internally-duplicated carbonic anhydrase from Dunaliella species by reconstitution of two separate domains

Mi-Ran Ki, Bashistha Kumar Kanth, Ki Ha Min, Jinwon Lee, Seung Pil Pack · PROCESS BIOCHEMISTRY · 2012

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Expression and Characterization of Codon-Optimized Carbonic Anhydrase from Dunaliella Species for CO2 Sequestration Application

Bashistha Kumar Kanth, Kiha Min, Shipra Kumari, Hancheol Jeon, Eon Seon Jin, Jinwon Lee, Seung Pil Pack · APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY · 2012

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Lens-free shadow image based high-throughput continuous cell monitoring technique

Geonsoo Jin, In-Hwa Yoo, Seung Pil Pack, Ji-Woon Yang, Un-Hwan Ha, Se-Hwan Paek, Sungkyu Seo · BIOSENSORS BIOELECTRONICS · 2012

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Expression of Codon-Optmized Phosphoenolpyruvate Carboxylase Gene from Glaciecola sp. HTCC2999 in Escherichia coli and its Application for C4 Chemical Production

Soohyun Park, Seung Pil Pack, Jinwon Lee · APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY · 2012

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2011

Anti-erythropoietin and anti-thrombopoietin antibodies induced after administration of recombinant human erythropoietin

Sug Kyun Shin 1, Seung Pil Pack, Jin-Gyo Oh, Nam Kyu Kang, Myung Hee Chang, Yoon Hee Chung, Sung-Jo Kim, Jong Wook Lee, Tae-Hwe Heo · INTERNATIONAL IMMUNOPHARMACOLOGY · 2011

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Thermostabilization of Bacillus circulans xylanase: Computational optimization of unstable residues based on thermal fluctuation analysis

Jeong Chan Joo, Seung Pil Pack, Yong Hwan Kim, Young Je Yoo · J. BIOTECHNOL. · 2011

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Quantitative analysis of specific target DNA oligomers using a DNA-immobilized packed-column system

Seung Pil Pack, Tae-Hwe Heo, Kamakshaiah Charyulu Devarayapalli, Keisuke Makino · ANAL. BIOANAL. CHEM. · 2011

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2010

Comparative Analysis of Screening Results from Various ELISA Formats Used for Detection of Anti-Erythropoietin Antibodies in Korean Patients

Sung Kyu HA, Seung-Ju YANG, Sug Kyun SHIN, Young-Il JO, Kyung-Min BAEK, Seung-Hwa HONG, Seung Pil PACK, Sung-Jo KIM, and Tae-Hwe HEO · BIOMOL. THER. · 2010

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Rules for computational design of enzymes to increase both the thermostability and the activity

Yeon-Jee Yoo, Jeong Chan Joo, So Yeon Hong, Ho-Nam Park, H.S. Yeon, Seung Pil Pack · JOURNAL OF BIOTECHNOLOGY · 2010

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Synthesis of 2'-deoxyoxanosine from 2'-deoxyguanosine, conversion to its phosphoramidite, and incorporation into oxanine-containing oligodeoxynucleotides.

Seung Pil Pack,Keisuke Makino · CURRENT PROTOCOLS IN NUCLEIC ACID CHEMISTRY / EDITED BY SERGE L. BEAUCAGE ... [ET AL.] · 2010

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Biomolecular response of oxanine in DNA strands to T4 polynucleotide kinase, T4 DNA ligase, and restriction enzymes

Seung Pil Pack, Akihiro Doi, Yoo Seong Choi, Tsutomu Kodaki, Keisuke Makino · BIOCHEM. BIOPHYS. RES. COMMUN. · 2010

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Comparison of the molecular influences of NO-induced lesions in DNA strands on the reactivity of polynucleotide kinases, DNA ligases and DNA polymerases

Akihiro Doi, Seung Pil Pack, Keisuke Makino · J. BIOCHEM. · 2010

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Thermostabilization of Bacillus circulans xylanase via computational design of a flexible surface cavity

Jeong Chan Joo, Subarna Pohkrel, Seung Pil Pack, Young Je Yoo · J. BIOTECHNOL. · 2010

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Accurate guanine:cytosine discrimination in T4 DNA ligase-based single nucleotide polymorphism analysis using an oxanine-containing ligation fragment

Seung Pil Pack, Akihiro Doi, Yoo Seong Choi, Hyong Bai Kim, Keisuke Makino · ANAL. BIOCHEM. · 2010

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2009

Comparison of the activities of bacterial and mammalian nucleotide excision repair systems for DNA-protein crosslinks

Toshiaki Nakano, Amir M H Salem, Hiroaki Terato, Seung Pil Pack, Keisuke Makino, Hiroshi Ide · NUCLEIC ACIDS SYMPOSIUM SERIES · 2009

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Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells

Toshiaki Nakano, Atsushi Katafuchi, Mayumi Matsubara, Hiroaki Terato, Tomohiro Tsuboi, Tasuku Masuda, Takahiro Tatsumoto, Seung Pil Pack, Keisuke Makino, Deborah L Croteau, Bennett Van Houten, Kenta Iijima, Hiroshi Tauchi, Hiroshi Ide · JOURNAL OF BIOLOGICAL CHEMISTRY · 2009

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Stabilization of the immobilized linkers and DNA probes for DNA microarray fabrication by end-capping of the remaining unreacted silanol on the glass

Nagendra Kumar Kamisetty, Seung Pil Pack, Mitsuru Nonogawa, Kazunari Yamada, Yasuko Yoshida, Tsutomu Kodaki , Keisuke Makino · JOURNAL OF BIOTECHNOLOGY · 2009

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Reinvestigation of the Molecular Influence of Hypoxanthine on the DNA Cleavage Efficiency of Restriction Endonucleases BglII, EcoRI and BamHI

Akihiro Doi, Seung Pil Pack, Tsutomu Kodaki, Keisuke Makino · JOURNAL OF BIOCHEMISTRY · 2009

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2008

Reactive oxygen species generation through NADH oxidation by pterin derivatives

Mitsuru Nonogawa, Toshiyuki Arai, Nobuyuki Endo, Seung Pil Pack, Tsutomu Kodaki, Keisuke Makino · NUCLEIC ACIDS SYMPOSIUM SERIES · 2008

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Efficient Preparation of xanthine-containing oligodeoxynucleotide from oxanine-containing oligodeoxynucleotide, catalyzed by Nα-acetyl-L-histidine

Akihiro Doi, Seung Pil Pack, Tsutomu Kodaki, Keisuke Makino · NUCLEIC ACIDS SYMPOSIUM SERIES · 2008

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Reactivity of oxanine: efficient fabrication of DNA microarray by using oxanine-containing DNA oligomer as probe molecule

Seung Pil Pack, Nagendra Kumar Kamisetty, Mitsuru Nonogawa, Tsutomu Kodaki, Keisuke Makino · NUCLEIC ACIDS SYMPOSIUM SERIES · 2008

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Temperature-gradient dependant detection of target DNA oligomers using DNA-immobilized open tubular capillary column

Nagendra Kumar Kamisetty, Seung Pil Pack, Kamakshaiah Charyulu Devarayapalli, Mitsuru Nonogawa, Tsutomo Kodaki, Keisuke Makino · NUCLEIC ACIDS SYMPOSIUM SERIES · 2008

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Repair of DNA-protein crosslink damage: Coordinated actions of nucleotide excision repair and homologous recombination

Hiroshi Ide, Toshiaki Nakano, Amir M H Salem, Hiroaki Terato, Seung Pil Pack, Keisuke Makino · NUCLEIC ACIDS SYMPOSIUM SERIES · 2008

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